Vol 77, No 2 - Abstracts

JSCS Vol 77, No. 2

Publication of this issue is financially co-supported by LUKOIL Srbija AD

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J. Serb. Chem. Soc. 77 (2) 131–140 (2012)

UDC 547–304.2+542.913+66.095.83–916.2; JSCS–4255; doi: 10.2298/JSC110408173R; Original scientific paper

Scalable methodologies for the synthesis of novel unsymmetrically substituted secondary AMines

GHEORGHE ROMAN

Department of Inorganic Polymers, Petru Poni Institute of Macromolecular Chemistry, 41A Aleea Gr. Ghica Vodă, Iaşi 700487, Romania

(Received 8 April, revised 2 July 2011)

Fast, easy, and scalable methodologies for the synthesis of unsymmetrically substituted secondary AMines containing naphthalene, indole, pyridine and imidazole moieties through reductive AMination were explored. The investigated operating procedures were successful on a 50- to 30-mmol scale, and present a high potential for up-scaling.

Keywords: reductive AMination; imine; secondary AMine; scalability.

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J. Serb. Chem. Soc. 77 (2) 141–146 (2012)

UDC 547–304.6+547.53+547.78+542.913; JSCS–4256; doi: 10.2298/JSC110321171O; Original scientific paper

The synthesis of some new hydrazone derivatives containing the benzothiazole moiety

AHMET ÖZDEMİR, GÜLHAN TURAN-ZITOUNI, ZAFER ASIM KAPLANCIKLI and MEHLİKA DİLEK ALTINTOP

Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 26470, Eskişehir, Turkey

(Received 21 March, revised 2 June 2011)

Hydrazones are an important class of compounds found in many synthetic products. Due to their importance in synthetic chemistry, the present article reports the synthesis of a new series of ten compounds based on the coupling of 2-oxo-3(2H)-benzothiazoleacetic acid, hydrazide and 2-thioxo-3(2H)--benzothiazoleacetic acid, hydrazide with different aldehydes. The structures of the synthesized compounds were confirmed by elemental analyses, IR, ¹H--NMR, ¹³C-NMR and FAB⁺–MS spectral data.

Keywords: hydrazone; 2-benzothiazolinone; 2-mercaptobenzothiazole; aromatic aldehydes.

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J. Serb. Chem. Soc. 77 (2) 147–157 (2012)

UDC 547.657.004.12:542.48:57–188; JSCS–4257; doi: 10.2298/JSC110616195G; Original scientific paper

Fractionation of complex mixtures of naphthenic acids, their characterization and biological activity

LJUBICA GRBOVIĆ, KSENIJA PAVLOVIĆ, BOJANA PREKODRAVAC, KSENIJA KUHAJDA, SLAVKO KEVREŠAN*, MIRJANA POPSAVIN, JELENA MILIĆ and VERA ĆIRIN-NOVTA

Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, Novi Sad, Serbia

*Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, Novi Sad, Serbia

(Received 16 June, revised 22 September 2011)

Naphthenic acids (NAs) are complex mixtures of cycloaliphatic and alkyl-substituted acyclic carboxylic acids, the overall characteristics of which are determined by the composition of the mixture. A complex mixture of NAs from a commercial fraction of atmospheric oil of the Vojvodina naphthenic crude oil “Velebit“ (Serbia) was separated into narrower fractions based on their acidity. Electrospray ionization mass spectrometry analysis of the fractions showed the occurrence of structural differentiation of the acids. By extraction at pH 3–5, about 50 % of the total mass of acids, consisting predominantly of tricyclic and bicyclic structures, was separated. Acids of lower acidity, (about 22 %), separated at pH 9 and 10, and their dominant constituents were acids with three-, four- and five-membered rings. A correlation was found between the dominant structure and the biological activity of the NAs of the fractions. The fraction extracted at pH 8, also with dominant bicyclic and tricyclic structures, showed the highest auxin and gibberellin activities.

Keywords: naphthenic acids; fractionation; structural analysis; biological activity.

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J. Serb. Chem. Soc. 77 (2) 159–176 (2012)

UDC 547.262+546.48:549.323.4–099; JSCS–4258; doi: 10.2298/JSC110330174R; Original scientific paper

Oxidative stress in rat liver during acute cadmium and ethanol intoxication

TATJANA RADOSAVLJEVIĆ, DUŠAN MLADENOVIĆ, MILICA NINKOVIĆ*, DANIJELA VUČEVIĆ, IVAN BORIČIĆ**, RADA JEŠIĆ-VUKIĆEVIĆ***, TAMARA ŠLJIVANČANIN, SRDJAN LOPIČIĆ and VERA TODOROVIĆ****

Department of Pathophysiology, School of Medicine, University of Belgrade, Serbia

*Institute for Medical Research, Military Medical Academy, Belgrade, Serbia

**Department of Pathology, School of Medicine, University of Belgrade, Serbia

***Institute for Digestive Diseases, Clinical Centre of Serbia, Belgrade, Serbia

****Faculty of Stomatology Pančevo, University Business Academy, Novi Sad, Serbia

(Received 30 March, revised 8 July 2011)

The aim of this study was to investigate the effects of binge drinking on the prooxidant/antioxidant system in rat liver in acute cadmium (Cd) intoxication. Male Wistar rats were used in the experiments. They were divided into the following groups: 1. control, 2. ethanol-treated group, in five subsequent doses of 2 g kg^-1, administered by an orogastric tube, 3. Cd-treated group in a single dose of 2.5 mg kg^-1, administered intraperitoneally, 4. group that received Cd 12 h after the last dose of ethanol. Blood and liver sAMples for determination of oxidative stress parAMeters, were collected 24 h after treatment. When administered in combination, ethanol and Cd induced a more pronounced increase in the serum and liver malondialdehyde levels than either of the substances alone (p<0.01). Liver manganese superoxide dismutase (MnSOD) activity was increased in both the ethanol- and Cd-treated groups (p<0.01), while liver copper/zinc superoxide dismutase (Cu/ZnSOD) activity was elevated in the Cd group only. However, when administered in combination, ethanol and Cd induced a more pronounced decrease in liver MnSOD and Cu/ZnSOD activity 24 h after treatment (p<0.01). Based on our study, it can be concluded that ethanol may act synergistically with Cd in inducing lipid peroxidation and reduction in liver SOD activity.

Keywords: ethanol; reactive oxygen species; cadmium; liver injury; rat.

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J. Serb. Chem. Soc. 77 (2) 177–185 (2011)

UDC 547.584+546.472+542.913:548.7:544.18; JSCS–4259; doi: 10.2298/JSC101209184T; Original scientific paper

Synthesis, crystal structure and computational chemistry research of the zinc(II) complex: [Zn(pt)(Biim)₂]

FEI TENG*, NAN JIANG**, ZHONGHUI WANG***, YUNCHENG CUI**and JIAJUN WANG**^,****

*Mathematics College of Jilin Normal University, Siping 136000, China

**Key Laboratory of Preparation and Application of Environmental Friendly Materials (Jilin Normal University), Ministry of Education, Chemistry Department of Jilin Normal University, Siping 136000, China

***Acrylonitrile Plant of PetroChina Jilin Petrochemical Company, Jilin 132021, China

****State Key Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry Jilin University, Changchun 130023, China

(Received 9 December 2010, revised 7 September 2011)

The title metal–organic coordination complex [Zn(pt)(Biim)₂] (pt = phthalate, benzene-1,2-dicarboxylate, Biim=2,2’-biimidazole) 1 was obtained by hydrothermal synthesis and characterized by single crystal X-ray diffraction. The complex crystallized as monoclinic, space group P2₁/n with a = 8.5466(15) Å, b = 11.760(2) Å, c = 20.829(4) Å, β = 95.56(2)º, V = 2083.5(6) Å³, Mr = 497.78, Dc = 1.587 g cm^-3, μ(MoK_α) = 1.226 mm^-1, F(000) = 1016, Z = 4, the final R = 0.0564 and wR = 0.1851 for 3656 observed reflections (I > 2s(I)). The complex was also investigated by elemental analysis, IR spectroscopy, themogravimetry and theoretical calculations.

Keywords: 2,2’-biimidazole; phthalic acid; zinc(II) complex; crystal structure; quantum chemistry.

Full Article - PDF 553 KB Available OnLine: 21. 11. 2011. Cited by

J. Serb. Chem. Soc. 77 (2) 187–199 (2012)

UDC 546.472’562+547.979.733+544.032.6:66.022.362; JSCS–4260; doi: 10.2298/JSC110310175Z; Original scientific paper

Zinc(II) and copper(II) complexes with pheophytin and mesoporphyrin and their stability to UV-B irradiation: Vis spectroscopy studies

JELENA B. ZVEZDANOVIĆ, DEJAN Z. MARKOVIĆ and SANJA M. MILENKOVIĆ

University of Niš, Faculty of Technology, Bulevar oslobodjenja 124, 16000 Leskovac, Serbia

(Received 10 March, revised 20 July 2011)

The stability of Zn(II) and Cu(II) complexes of porphyrin derivatives (pheophytin and mesoporphyrin) to UV-B irradiation was studied by absorbance spectroscopy in 95 % ethanol. The chosen porphyrins and their heavy metal complexes underwent first-order photochemical decomposition. In general, pheophytin was more stable than mesoporphyrin to UV-B irradiation. Moreover, the stabilities of the Zn(II) complexes were lower than those of the Cu(II)-complexes for both pheophytin and mesoporphyrin. However, while the Cu(II)-complex with pheophytin was more stable than the one with mesoporphyrin, the situation was vice versa for the Zn(II)-complexes.

Keywords: pheophytin; mesoporphyrin; heavy metal; complexes; UV-B kinetics.

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J. Serb. Chem. Soc. 77 (2) 201–210 (2012)

UDC 547.586.1/.7+544.351+543.42+544.77.022.532; JSCS–4261; doi: 10.2298/JSC110121182N; Original scientific paper

Interactions of short chain phenylalkanoic acids within ionic surfactant micelles in aqueous media

Kashif Naeem, Syed W. H. Shah*, Bushra Naseem** and Syed S. Shah*

Central Analytical Facility Division, PINSTECH, PO Nilore, IslAMabad 45650, Pakistan

*Department of Chemistry, Hazara University, Mansehra, Pakistan

**Department of Chemistry, Lahore College for Women University, Lahore, Pakistan

(Received 21 January, revised 10 August 2011)

The solubilization and interactions of phenylalkanoic acids induced by the cationic surfactant, cetyltrimethylAMmonium bromide (CTAB) and the anionic surfactant sodium dodecyl sulfate (SDS) was investigated spectrophotometrically at 25.0 °C. The UV spectra of the additives (acids) were measured with and without surfactant above and below the critical micelle concentration (cmc) of the surfactant. The presence of an alkyl chain in phenylalkanoic acids was responsible for hydrophobic interactions resulting in a shift of the spectra towards longer wavelengths (red shift). The value of partition coefficient (K_X) between the bulk water and surfactant micelles and, in turn, the standard free energy change of solubilization (DG_p^ө) were also estimated by measuring the differential absorbance (DA) of the additives in micellar solutions.

Keywords: alkanoic acids; solubilization; cmc; CTAB; SDS.

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J. Serb. Chem. Soc. 77 (2) 211–224 (2012)

UDC 547.478+546.11+544.35:542.8; JSCS–4262; doi: 10.2298/JSC112106185J Original scientific paper

On the kinetics of the hydrogen evolution reaction on Ni–MoO_x composite catalysts in alkaline solutions

BORKA M. JOVIĆ, UROŠ Č. LAČNJEVAC, VLADIMIR D. JOVIĆ, LJILJANA M. GAJIĆ-KRSTAJIĆ* and NEDELJKO V. KRSTAJIĆ**

Institute for Multidisciplinary Research, University of Belgrade, P. O. Box 33, 11030 Belgrade, Serbia

*Institute of Technical Sciences SASA, Knez Mihajlova 35, 11000 Belgrade, Serbia

**Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11000 Belgrade, Serbia

(Received 21 June, revised 19 September 2011)

MoO₃ particles were co-deposited with Ni onto smooth or rough Ni supports from modified Watt baths of different compositions. Morphology and composition of the electrodeposits were characterized by means of cyclic voltAMmetry, X-ray diffraction analysis, scanning electron microscopy, transmission electron microscopy and energy dispersive X-ray spectroscopy. The electrocatalytic activity of the composite catalysts for H₂ evolution in alkaline solutions was determined by quasi-stationary polarization curves. Activity increases with MoO_x content in the Ni deposit up to a limiting value. The composite Ni–MoO_x catalysts exhibited high catalytic activity, similar to that of a commercial Ni–RuO₂ catalyst. Stability tests showed that the Ni–MoO_x co-deposits were stable under constant current conditions and exhibited excellent tolerance to repeated short-circuiting.

Keywords: hydrogen evolution; nickel; molybdenum trioxide; composite catalyst; co-deposition.

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J. Serb. Chem. Soc. 77 (2) 225–234 (2012)

UDC 677.21+539.24+546.57:615.281–188+66.022.362; JSCS–4263; doi: 10.2298/JSC110505167L; Original scientific paper

A study of the antibacterial activity and stability of dyed cotton fabrics modified with different forms of silver

VESNA LAZIĆ, ZORAN ŠAPONJIĆ*, VESNA VODNIK*, SUZANA DIMITRIJEVIĆ**, PETAR JOVANČIĆ, JOVAN NEDELJKOVIĆ* and MAJA RADETIĆ

Textile Engineering Department, Faculty of Technology and Metallurgy, Karnegijeva 4, 11000 Belgrade, Serbia

*Vinča Institute of Nuclear Sciences, P. O. Box 522, 11001 Belgrade, Serbia

**Department of Bioengineering and Biotechnology, Faculty of Technology and Metallurgy, Karnegijeva 4, 11000 Belgrade, Serbia

(Received 5 May, revised 31 May 2011)

This study compares the effect of colloidal silver nanoparticles and the commercial RUCO-BAC AGP agent with silver chloride as the active component on the antibacterial activity of dyed cotton fabrics. Cotton fabrics were dyed with vat dyes Bezanthren Olive T and Bezanthren Grey FFB. The antibacterial activities of the silver-loaded dyed cotton fabrics were tested against the GrAM-positive bacterium Staphylococcus aureus and the GrAM-negative bacterium Escherichia coli. Unlike RUCO-BAC AGP, the synthesized silver nanoparticles deposited onto the dyed cotton fabrics provided maximum bacteria reduction, independent of the applied dye. The stability of the modified cotton fabrics was analyzed in artificial sweat at pH 5.5 and 8.0. Approximately the sAMe AMount of silver was released from the differently modified cotton fabrics in artificial sweat. Larger AMounts of silver were released in the sweat at pH 8.0.

Keywords: cotton; silver nanoparticles; RUCO-BAC AGP; antibacterial efficiency; artificial sweat.

Full Article - PDF 267 KB Available OnLine: 17. 11. 2011. Cited by

J. Serb. Chem. Soc. 77 (2) 235–246 (2012)

UDC 628.3+667.281+547.79:66.099.72; JSCS–4264; doi: 10.2298/JSC110315165A; Original scientific paper

A central composite design for the optimization of the removal of the azo dye, methyl orange, from waste water using the Fenton reaction

Mahsa AzAMi, Morteza BahrAM, Sirous Nouri and Abdolhosein Naseri*

Department of Chemistry, Faculty of Science, Urmia University, Urmia, Iran

*Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, 51666–16471, Tabriz, Iran

(Received 15 March, revised 9 May 2011)

In this study the degradation of Methyl Orange, using Fenton reaction was studied and optimized using central composite design as a response surface methodology. The effects of various experimental parAMeters in this reaction were investigated using the central composite design. 28 experiments, with 4 factors and 5 levels for each factor were designed. These factors (or variables) were: the initial concentration of Fe(II), the initial concentration of H₂O₂, the initial concentration of oxalate and the reaction time. A full-quadratic polynomial equation between the percentage of dye degradation (as the response) and the studied parAMeters was established. After removing the non-significant variables from the model, response surface method was used to obtain the optimum conditions. The optimum ranges of variables were: 0.25–0.35 mM for the initial concentration of Fe(II), 5–17 mM for the initial concentration of H₂O₂, 4–9 mM for the initial concentration of oxalate, and 50–80 min for the reaction time. In addition, the results of extra experiments showed that these optimized values can be used for real sAMples and lead to a high value for the response.

Keywords: design of experiments; decolourization; Fenton reaction; Methyl Orange.

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J. Serb. Chem. Soc. 77 (2) 247–255 (2012)

UDC 550.4:597+56.022:551.352.1:552.63(489); JSCS–4265; doi: 10.2298/JSC110404178P; Original scientific paper

Iridium anomaly in the Cretaceous–Paleogene boundary at Højerup (Stevns Klint, Denmark) and Woodside Creek (New Zealand): the question of an enormous proportion of extraterrestrial component

PAVLE I. PREMOVIĆ, BUDIMIR S. ILIĆ* and MILOŠ G. ĐORĐEVIĆ

Laboratory for Geochemistry, Cosmochemistry and Astrochemistry, University of Niš, P. O. Box 224, 18000 Niš, Serbia

*Department of Pharmacy, Faculty of Medicine, University of Niš, 18000 Niš, Serbia

(Received 4 April, revised 8 August 2011)

The Cretaceous–Paleogene boundary clays at Højerup and Woodside Creek show anomalous enrichments of iridium compared with the marine sedimentary rocks. For the average iridium content of 465 ppb in CI chondrite the estimate of the carbonaceous chondritic proportions in the decarbonated iridium-rich boundary layers, based on the integrated iridium fluencies, is about 26 % at Højerup and 65 % at Woodside Creek. These proportions are most likely too high due to a significant Ir influx from the nearby marine or continental site to these sections.

Keywords: Fish Clay; Woodside Creek; iridium; carbonaceous chondrite.

Full Article - PDF 362 KB Available OnLine: 21. 11. 2011. Cited by

J. Serb. Chem. Soc. 77 (2) 257–258 (2012)

Errata (printed version only)

Issue No. 1 (2012), Vol. 77: Paper Nos. JSCS-4247 and JSCS-4248

Full Article - PDF 133 KB

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